Which of the following groups must be represented in an IRB?

To ensure that the Institutional Review Board (IRB) operates effectively, it is crucial to have a diverse representation of members. Having at least one scientist and one non-scientist promotes a comprehensive review process, allowing for the consideration of both research methodologies and the implications of the research on individuals and the community.

The presence of a scientist is essential for understanding the technical aspects of the research, including its methodology, potential risks, and benefits. Conversely, the inclusion of a non-scientist helps to ensure that ethical considerations and societal perspectives are adequately addressed. This balance between scientific and ethical viewpoints is instrumental in evaluating research proposals in a way that protects the rights and welfare of participants.

This diverse representation is a fundamental principle outlined by federal regulations governing IRBs, which aim for a fair and thoughtful review process that encompasses both scientific rigor and ethical responsibilities. Thus, the requirement for at least one scientist and one non-scientist is critical to the IRB's mission of safeguarding human research participants.